The pesticide industry is a crucial agricultural sector in many countries. The negative effects of pesticides on the environment is due to the generation of huge amounts of effluents. In order to study the effect of pesticide industry effluents on the diversity of native flora in the vicinity of India Pesticides Limited, located in Sandila, Uttar Pradesh, extensive field surveys were conducted. Results of the present study revealed that around 110 plant species belonging to 49 families were growing luxuriantly without showing any phytotoxic effect of pesticide industry effluents. Among the collected plants maximum number of species belonged to the family Asteraceae, followed by Fabaceae, Solanaceae, Poaceae, Acanthaceae, Convolvulaceae, Lamiceae, and Polygonaceae. As per taxonomic studies, 83 plant species belonged to dicotyledons, while only 27 species were monocotyledons. Further work on the toxic effects of the pesticide industry effluents in the internal metabolic adaptation of some dominant species is in progress.